Multiplex padlock targeted sequencing reveals human hypermutable CpG variations
نویسندگان
چکیده
منابع مشابه
Multiplex padlock targeted sequencing reveals human hypermutable CpG variations.
Utilizing the full power of next-generation sequencing often requires the ability to perform large-scale multiplex enrichment of many specific genomic loci in multiple samples. Several technologies have been recently developed but await substantial improvements. We report the 10,000-fold improvement of a previously developed padlock-based approach, and apply the assay to identifying genetic var...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2009
ISSN: 1088-9051
DOI: 10.1101/gr.092213.109